3-Pyridinemethanamine,N-[5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-

Name	Pexidartinib
Synonyms	PLX-3397 Pexidartinib 5-((5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl) N-[5-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-3-pyridinemethanamine 3-Pyridinemethanamine,N-[5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-
CAS	1029044-16-3

Molecular Formula	C20H15ClF3N5
Molar Mass	417.8148
Density	1.458±0.06 g/cm3(Predicted)
Solubility	DMSO: ≥ 30 mg/mL
Appearance	Form solid, color White
pKa	12.81±0.40(Predicted)
Storage Condition	-20°C
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Physical and Chemical Properties	Bioactive Pexidartinib (PLX3397) is an orally effective multi-target CSF-1R,Kit (c-Kit), and FLT3 receptor tyrosine kinase inhibitor with IC50 of 20 nM, 10 nM, and 160 nM, respectively. Pexidartinib (PLX3397) can induce apoptosis and necrosis and has antitumor activity. Phase 3.

Last Update：2024-01-02 23:10:35

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Product Name: Pexidartinib Visit Supplier Webpage Request for quotation
CAS: 1029044-16-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

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3-Pyridinemethanamine,N-[5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)- Request for Quotation